Left Ventricular Myocardial Performance Index and Its Relationship with Presystolic Wave in Prediabetic Patients

Introduction: In this study, we aimed to investigate the effect of prediabetes on the cardiovascular system and the relationship between MPI and PSW by using myocardial performance index (MPI) and presystolic wave (PSW) and the usability of both parameters as a screening test.
Methods: A total of 113 participants, that is, 59 prediabetic patients and 54 healthy volunteers, aged 18–79 years, who applied to cardiology and endocrinology polyclinics between March 2020 and September 2020, were included in the present study. The groups were compared in demographic and clinical data, left ventricular functions, left ventricular MPI, PSW, and laboratory results.
Results: Left ventricular diastolic dysfunction (p=0.001), MPI (p<0.001), and PSW (p=0.003) were higher in the prediabetic group. A positive correlation was observed between fasting blood glucose and MPI index (r=0.509, p<0.001) and between PSW and MPI (r=0.405, p=0.001).
Discussion and Conclusion: This study is the first in the literature to examine the effects of prediabetes on the cardiovascular system using MPI and PSW. We think that these parameters may be associated with left ventricular diastolic dysfunction in prediabetics.

Keywords: Diastolic dysfunction; Myocardial performance index; Prediabetes; Presystolic wave