Targeted Temperature Management After Cardiovascular Collapse Secondary to Contrast Agent Anaphylaxis

Anaphylaxis is the most critical type of contrast agent (CA)–related hypersensitivity. In this report, we present a case of a 26-year-old female who experienced anaphylaxis during contrast-enhanced computerized tomography scanning. After cardiovascular collapse with asystole on the electrocardiogram, the patient was resuscitated. She received standard post-resuscitation care and an additional targeted temperature management (TTM) for clinical and radiological diagnoses of cerebral ischemia after the return of spontaneous circulation. After 19 days of treatment in the intensive care unit, she regained full consciousness. TTM can be kept in mind as an additional mode of therapy, irrespective of initial arrest rhythm in the treatment of comatose patients after cardiac arrest and cerebral hypoxia resulting from CM anaphylaxis.

Keywords: Anaphylaxis; Cardiovascular collapse; Targeted temperature management